Background. The effect of antiretroviral therapy (ART) interruption or intensification on health-related quality of life (HRQoL) in advanced HIV patients is unknown.
Objective. To assess the impact of temporary treatment interruption and intensification of ART on HRQoL.
Design. A 2 x 2 factorial open label randomized controlled trial.
Setting. Hospitals in the United States, Canada, and the United Kingdom.
Over the past decade, the ownership and control of China's corporate sector has finally begun to depart fundamentally from patterns typical in the socialist past. Students of corporate governance have watched these changes with an intense curiosity about their impact on firm performance. Students of comparative economic institutions have examined them for hints of a new variety of Asian capitalism and have sought to anticipate China's international competitiveness and impact.
Getting to Zero takes on the much-debated goal of nuclear zero—exploring the serious policy questions raised by nuclear disarmament and suggesting practical steps for the nuclear weapon states to take to achieve it.
It documents the successes and failures of six decades of attempts to control nuclear weapons proliferation and, within this context, asks the urgent questions that world leaders, politicians, NGOs, and scholars must address in the years ahead.
By deemphasizing the role of nuclear weapons in US security policy, the 2010 Nuclear Posture Review (NPR) could lead India to slow or halt the growth of its nuclear weapons capabilities and to adopt a less assertive nuclear doctrine; however, the NPR is unlikely to have this effect on India's nuclear program. This is the case for two reasons. First, Indian leaders do not seek to emulate US nuclear behavior; they formulate policy based primarily on their assessment of the security threats facing India. Second, Indians do not think that the NPR augurs major changes in US nuclear policy.
This article argues that Congress should authorize and fund a National Academies risk analysis of nuclear deterrence. It also explains how risk analysis is able to tease much more information out of the available data – which clearly does not yet involve a failure of nuclear deterrence – than might first appear possible.
"Alexander Betts is one of a handful of scholars who have mastered the complex field of Global Migration Governance. This large and impressive volume covers the topic from every conceivable angle, and it gets the difficult mix of empirical analysis and policy recommendation right. As the global conversation about migration governance continues over the coming years, this work will remain the standard reference."--Randall Hansen, Research Chair in Political Science, University of Toronto
What accounts for variation in the durability of authoritarian regimes in the post-colonial Middle East? This working paper presents a new explanation that underscores how the geopolitical environment mediated outcomes of domestic conflicts pitting early rulers against social opposition.
Recent breakdowns in American national security have exposed the weaknesses of the nation's vast overlapping security and foreign policy bureaucracy and the often dysfunctional interagency process. In the literature of national security studies, however, surprisingly little attention is given to the specific dynamics or underlying organizational cultures that often drive the bureaucratic politics of U.S. security policy.
The internet is enabling new approaches to public diplomacy. The Digital Outreach Team at the US Department of State is one such initiative, aiming to engage directly with citizens in the Middle East through posting messages about US foreign policy on popular Arabic, Urdu, and Persian language internet forums. This permits them to present the US administration's views on issues related to American foreign policy in a transparent manner. This case study assesses the process and reach of this new method of internet diplomacy.
Numerous countries have transitioned away from state socialism since the fall of Communism in the Soviet Union and its satellite states two decades ago. At the core of this phenomenon, suggests Andrew G. Walder, is “a radical change in the definition, enforcement, and allocation of various rights over property.” In the chapter “Transitions from State Socialism: A Property Rights Perspective” (The Sociology of Economic Life, 2011), Walder examines property rights changes within the context of the transition from state socialism in Hungary, China, and Vietnam.