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From the 1950s through the 1970s, the success of antibiotics and vaccines in controlling or eradicating infectious diseases (ID) worldwide resulted in decreased emphasis on development of ID therapeutics. The emergence in the past three decades of HIV, SARS, West Nile, avian flu, swine flu, Ebola, and the potential for bioterrorist attacks has reversed this trend and renewed interest in treatment and prophylaxis of ID. Unfortunately, because many diseases are prevalent primarily in developing nations (e.g., malaria, TB, Chagas), potential sales of bioterrorist pathogens are limited mainly to orders for government stockpiles (e.g., anthrax, smallpox, botulinum toxin), and the cost of anti-infective clinical trials is high, traditional large pharmaceutical companies have cut back R&D resources in this arena. To combat this investment shortfall, a new paradigm has emerged where public-private partnerships between the NIH, World Health Organization, private foundations, academia, and non-profits, are beginning to function like pharmaceutical companies to advance the development of promising ID drugs, even when there is little opportunity for profit. This talk will discuss the growing need for ID therapeutics, present some new models for discovering and developing them, and provide examples of public-private partnerships that have advanced therapeutics for specific infectious diseases.


About the speaker: Dr. Jon C. Mirsalis is Managing Director of the Biosciences Division and Executive Director of Preclinical Development at SRI International in Menlo Park, CA. Dr. Mirsalis is an internationally recognized expert in the development of drugs for infectious diseases. He manages two large programs for the National Institute of Allergy and Infectious Diseases (NIAID) for the development of promising therapeutics for the prevention and treatment of a broad range of infectious diseases including TB, malaria, influenza, polio, anthrax, plague, and Ebola. He has personally been involved in the development of over 50 therapeutics that have entered clinical trials and several have already reached the market. Before joining SRI in 1981, Dr. Mirsalis was a postdoctoral fellow at the Chemical Industry Institute of Toxicology, where he developed the in vivo-in vitro hepatocyte DNA repair assay, which is now widely used as a screen for potential carcinogens by government and industry. He is the author of over 140 publications and abstracts. Dr. Mirsalis received his B.S. degree in zoology/molecular biology from Kent State University, his M.S. degree in genetics from North Carolina State University, and holds Ph.D. degrees in toxicology and genetics from North Carolina State University. Dr. Mirsalis has an adjunct faculty appointment with the University of California-Santa Cruz, where he lectures regularly on genetic toxicology and carcinogenesis. He has recently served on the Board of Scientific Councilors for the National Toxicology Program, the Advisory Board for the Critical Path Institute, and is a past member of the FDA’s Over-the-Country Product Review Committee. Dr. Mirsalis has been certified by the American Board of Toxicology since 1983.

CISAC Conference Room

Jon Mirsalis Managing Director, Biosciences Division Speaker SRI International
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China 2.0 Overview | Past Events

China 2.0 Beijing 2013 Forum at The Stanford Center at Peking University

Keynote Speakers
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Ambassador Gary F. Locke



Gary F. Locke

U.S. Ambassador to the People's Republic of China
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Joseph Chen, Chairman and CEO of Renren, Inc.



Joseph Chen
Chairman and CEO of Renren, Inc.
Past China 2.0 Speakers
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Past China 2.0 Speakers

The Stanford Program on Regions of Innovation and Entrepreneurship (SPRIE) of the Stanford Graduate School of Business will host a China 2.0 Forum in Beijing on Friday, April 12, 2013 at the Stanford Center at Peking University (SCPKU).

While ample capital was raised in recent years, China's VC and PE markets are now facing a flight to quality. Exits are constrained both in China and abroad. At the same time, rapid changes in social, mobile, analytics, and cloud are changing the landscape for business models and strategy. Which ideas and entrepreneurs in China will break out and why? Will the shift to mobile platforms challenge incumbent players and unlock a new generation of digital economy powerhouses? How are developments in China connected with the global digital economy?

This invitation-only half-day event will bring together current and rising leaders from China’s tech, entrepreneur, and investor communities to discuss topics including:

  • Big Data: A New Frontier
  • Mobile Apps: The Next $100+ Billion Market?
  • Fueling Firm Growth: VC and Entrepreneur Dialogue
  • China and the Global Digital Economy

The Forum will feature keynote speakers, panels, and interactive sessions followed by a networking reception. Attendees will also be briefed on a recent Stanford study on alumni entrepreneurship and have the opportunity to participate in new research led by SPRIE on entrepreneurship patterns in China.


Agenda

1:30 – 2:00 pm Registration
2:00 – 2:10 pm Opening Remarks and Video
Marguerite Gong Hancock & Duncan Clark, China 2.0 Forum Co-Chairs
2:10 – 2:40 pm Keynote: “China and the Global Digital Economy
Gary Locke, U.S. Ambassador to the People’s Republic of China
2:40 – 3:25 pm Panel Discussion: “Mobile Apps: The Next $100+ Billion Market?”
Amy Gu, General Manager, China – Evernote Corporation
David Liu, Founder and CEO – RedAtoms
Junde YU, Vice President at APAC, App Annie
Moderator: Richard Lim, Managing Director & Co-Founder, GSR Ventures
3:25 – 3:40 pm Briefing: Stanford Entrepreneurship Research Results and New China 2.0 Research
Marguerite Gong Hancock and Duncan Clark
3:40 – 4:05 pm Tea Break sponsored by Tencent
4:05 – 4:40 pm Panel Discussion: “Big Data: A New Frontier”
Alex Cheng, Vice President at Baidu
ZENG Ming, Chief Strategy Officer – Alibaba Group
4:40 – 5:25 pm

Panel Discussion: “Fueling Firm Growth: VC & Entrepreneur Dialogue”
Ming LEI, Co-Founder – Kuwo, Inc.
Annabelle Yu Long, Member of Bertelsmann Group Management Committee; Chief Executive – Bertelsmann China Corporate Centre; Managing Director – Bertelsmann Asia Investments
LU Dong, Founder and CEO – La Miu China
Hans Tung, Managing Partner – Qiming Ventures

5:25 – 5:55 pm Keynote: Simple Math for Multiplying Impact:  How to do better in work and philanthropy
Joseph Chen, Founder, Chairman and CEO of RenRen, Inc.
5:55 – 6:00 pm Closing Remarks
Marguerite Hancock & Duncan Clark, China 2.0 Forum Co-Chairs
6:00 – 7:00 pm Networking Reception sponsored by GSR Ventures

Speakers

  • Alex Cheng, Vice President at Baidu
  • Duncan Clark, Chairman, BDA China & Senior Advisor to China 2.0, SPRIE, Stanford Graduate School of Business
  • DONG Lu (MBA ’04), Founder & CEO, La Miu
  • Amy Gu (MBA '09), General Manager, China, Evernote
  • Marguerite Gong Hancock, Associate Director, SPRIE, Stanford Graduate School of Business
  • Ming LEI (MBA ‘05), Co-Founder, Kuwo
  • Richard Lim (MBA ‘88), Managing Director & Co-Founder, GSR Ventures
  • Annabelle Yu Long (MBA ’05), Member of Bertelsmann Group Management Committee; Chief Executive, Bertelsmann China Corporate Centre; Managing Director, Bertelsmann Asia Investments
  • David Liu (MS ‘98, PhD ‘03), Founder and CEO, RedAtoms
  • Hans Tung (BS ‘93), Managing Partner, Qiming Ventures
  • Junde YU, Vice President, APAC, App Annie
  • ZENG Ming, Chief Strategy Officer, Alibaba Group

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SCPKU at night

Venue

The Stanford Center at Peking University is located on the site of a former imperial palace on the northeast area of the Peking University campus. Opened in March 2012, SCPKU uniquely combines a traditional Chinese wood courtyard building with a modern, state-of-the-art facility. For map and directions, please click here.

 

Map of Route from Peking University's Southeast Gate to SCPKU


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Platinum Sponsor
Networking Reception
 

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GSR Ventures
GSR Ventures is an early-stage venture capital firm building world-class technology companies in China. The firm invests primarily in the Internet, wireless, green technology and semiconductors sectors. Founded in 2004, GSR has more than 50 companies in its portfolio and more than $1 billion under management.


Gold Sponsor
Tea Break
 

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Tencent
Founded in November, 1998, Tencent has grown into one of China's largest provider of comprehensive Internet services. It went public on the main board of the Hong Kong Stock Exchange in June 2004. Tencent aims to enrich the interactive online experience of Internet users by providing a comprehensive range of Internet and wireless value-added services. Through its various online platforms, including Instant Messaging QQ, web portal QQ.com, the QQ Game Platform under Tencent Games, multi-media social networking service Qzone and wireless portal, Tencent services the largest online community in China and fulfills the user’s needs for communication, information, entertainment and e-Commerce on the Internet.


Silver Sponsors
 

 
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Alibaba Group is a family of Internet-based businesses which makes it easy for anyone to buy or sell online anywhere in the world. Since its inception, it has developed leading businesses in consumer e-commerce, online payment, business-to-business marketplaces and cloud computing, reaching Internet users in more than 240 countries and regions. Alibaba Group consists of 25 business units and is focused on fostering the development of an open, collaborative and prosperous e-commerce ecosystem.
 
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App Annie is the industry leader in app store analytics and market intelligence for the global app economy. More than 80 percent of the Top 100 iOS publishers use its services, and more than 200,000 apps from over 24,000 unique app publishers rely on App Annie Analytics to track their downloads, revenues, rankings and reviews. App Annie is a privately held global company with offices in Beijing, San Francisco, Hong Kong, Tokyo, and London.
 
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Baidu is the largest Chinese-language search engine. Since its founding in 2000, Baidu's mission has been to provide the best and most equitable way for people to find whatever they're looking for online. Powered by world-class technology and a deep understanding of Chinese language and culture, Baidu now provides intelligent and relevant search results to over five hundred million users. In addition, Baidu has become the largest media platform in China for businesses to effectively reach potential customers online. Baidu continues to innovate to fulfill the needs of users, leveraging it unrivaled cloud infrastructure to deliver the best experience on any device as the shift toward mobile Internet continues in China.
 
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CIB Productions
CIB Productions is a Beijing-based television and video production services company staffed with international talent experienced in producing to broadcast standards. Our services include high-end corporate video production, production services for broadcasters and visiting production companies and filming of live events.
 
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Qiming Venture Partners
Qiming Venture Partners invests in young, fast-growing companies across China in the media and internet, IT, consumer and retail, healthcare, and clean technology sectors. It is an early to growth stage venture capital firm with offices in Shanghai, Beijing and Hong Kong. Founded in 2006, Qiming currently manages five funds with over $1.1 billion in assets.
 
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RedAtoms is a mobile social game company committed to producing well-crafted games that connect people. Headquartered in China and with locations in Hong Kong, Tokyo and San Francisco, RedAtoms has produced top ranking card battle and music games, where millions of players interact with each other on a daily basis.

 

About the China 2.0 Initiative

China 2.0 is a research and education initiative led by SPRIE at the Stanford Graduate School of Business focusing on the drivers and dynamics of the rise of China’s internet industry and its global implications. China 2.0 is a bridge between Stanford/Silicon Valley and China, academia and industry, and current and next generation entrepreneurs on both sides of the Pacific.

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Participants at a past China 2.0 event

Past China 2.0 Events

The Stanford Center at Peking University
(see above for link to map and directions)

Workshops

Shorenstein APARC
Encina Hall C333
616 Serra Street
Stanford, CA 94305-6055

(650) 724-1320 (650) 723-6530
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2013 Visiting Scholar
LEE,_Dong-Wook_3x4.jpg PhD

Dong-Wook Lee is a visiting scholar at the Walter H. Shorenstein Asia-Pacific Research Center (Shorenstein APARC).

Lee has worked for many different divisions at the Republic of Korea’s Ministry of Knowledge Economy, in various fields such as automobiles and shipbuilding, overseas resources development, inter-Korean economic cooperation, industrial complex development, and emerging industries policies, to name a few. At the ministry, he has played a central role in developing industry related policies, enhancing the competitiveness of Korea's industries, strengthening cooperation between North and South Korea, and promoting industrial convergence.

Before Lee came to Shorenstein APARC, he was a director general in charge of the Korea Trade-Investment Promotion Agency (KOTRA)’s Foreign Investor Support Office to attract foreign direct investment. He has served as a public official for more than 20 years since passing the Examination for Higher Civil Service (finance and economy) in 1991.

Lee acquired a BA in business management from Yonsei University and an MA in public administration from Seoul National University. He earned a PhD in economics from KonKuk University in February 2012.

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In his State of the Union address on February 12 President Obama announced that the US will set up a Transatlantic Trade and Investment Partnership with the European Union. The US and the EU will soon start negotiations to create the world’s largest free trade area. The agreement will eliminate tariff barriers and harmonize regulatory and technical standards. It is argued that this will add up to two percent to GDP. The US and the EU already trade goods and services worth $ 2.7 billion per day. This seminar will discuss the politics and economics of such an agreement.

This event is part of The Europe Center's series on the "European and Global Economic Crisis."

Reuben W. Hills Conference Room

Encina Hall
Stanford University
Stanford, CA 94305

(650) 723-0249 (650) 723-0089
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Senior Research Scholar at The Europe Center
cc3.jpg PhD

Christophe Crombez is a political economist who specializes in European Union (EU) politics and business-government relations in Europe. His research focuses on EU institutions and their impact on policies, EU institutional reform, lobbying, party politics, and parliamentary government.

Crombez is Senior Research Scholar at The Europe Center at the Freeman Spogli Institute for International Studies at Stanford University (since 1999). He teaches Introduction to European Studies and The Future of the EU in Stanford’s International Relations Program, and is responsible for the Minor in European Studies and the Undergraduate Internship Program in Europe.

Furthermore, Crombez is Professor of Political Economy at the Faculty of Economics and Business at KU Leuven in Belgium (since 1994). His teaching responsibilities in Leuven include Political Business Strategy and Applied Game Theory. He is Vice-Chair for Research at the Department for Managerial Economics, Strategy and Innovation.

Crombez has also held visiting positions at the following universities and research institutes: the Istituto Italiano di Scienze Umane, in Florence, Italy, in Spring 2008; the Department of Political Science at the University of Florence, Italy, in Spring 2004; the Department of Political Science at the University of Michigan, in Winter 2003; the Kellogg Graduate School of Management at Northwestern University, Illinois, in Spring 1998; the Department of Political Science at the University of Illinois at Urbana-Champaign in Summer 1998; the European University Institute in Florence, Italy, in Spring 1997; the University of Antwerp, Belgium, in Spring 1996; and Leti University in St. Petersburg, Russia, in Fall 1995.

Crombez obtained a B.A. in Applied Economics, Finance, from KU Leuven in 1989, and a Ph.D. in Business, Political Economics, from Stanford University in 1994.

Christophe Crombez Speaker
Timothy Josling Speaker
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Africa owns 60% of the world’s uncultivated land suited for crop production, but accounts for 30% of the world’s malnourished and only 3% of global agricultural exports. If there is one thing global agricultural policy experts Paul Collier and Derek Byerlee can agree on, it’s that Africa’s food system is struggling.Their different views on the causes and investment solutions to put Africa on a more prosperous and food secure path made for a provocative discussion at a symposium hosted last week by Stanford University’s Center on Food Security and the Environment.

Collier, a distinguished economist and author of the award-winning book “The Bottom Billion”, was direct in his opening remarks.

“Smallholder agriculture has been a persistent productivity disaster for Africa,” said Collier. “Despite a huge land area to population ratio and higher proportion of its labor force engaged in food production, Africa is still not able to feed itself. The smallholder business model of the last 50 years is fundamentally flawed…maybe it is time for a Plan B.”

African agricultural productivity remains astoundingly low and stagnant at about $500 per person per year. His solution: debunk the ‘myth of the efficient peasant’ and rural romanticism and support commercial agriculture and urban growth.

Commercial agriculture reaps economies of scale that provide advantages often beyond reach for smallholder farmers yet are critical to agricultural production in Africa—risk finance, liquidity, technology, logistics, and knowledge of markets. Collier points to the success of Brazil and Thailand—two emerging economies that differ in scale of commercial organization, but have become major agricultural exporting countries.

Byerlee, a renowned economist and director of the 2008 World Development Report, agreed with Collier that commercial agriculture is likely Africa’s future, but that market-oriented smallholder farmers will play the lead role.

“We have much to learn from emerging business models,” said Byerlee. “Smallholders and agribusiness have complementary assets that can contribute to commercial agriculture, and states and investors must help facilitate smallholder inclusion in these models.”

Byerlee noted that the choice between small-scale or large-scale production models depend on transaction costs and type of commodity, and are context specific. Small- to medium scale production is best suited to most types of products in Africa especially food staples and many labor intensive products (e.g, diary). This follows the example of Thailand that not only has succeeded in food production but alone exports more than the value of all sub-Saharan Africa. Value chains that require stronger coordination with processing and shipping (e.g., sugar and palm oil), demand market standards (e.g, export horticulture) or are taking pioneering risks (e.g., new crops in new areas) may be better suited for large-scale production. Benefits may still be large if they create good jobs—a major challenge for Africa’s future.

Where to invest in Africa’s future?

"Young Africans are voting with their feet in droves to leave smallholder agriculture because it is impoverishing and boring, “ said Collier. “The economic tragedy for Africa is that cities haven’t been the engines of economic opportunity and wage employment.”

Collier argued investments in cities over agriculture are needed to prepare for an urban future and must be done quickly due to one dangerous fact—climate change.

“Climate change is the train coming down the tracks and it is already happening in Africa,” warned Collier. “The continuing deterioration of African agriculture is already set in stone. The last 50 years of carbon emissions are going to continue to devastate Africa’s climate over the next 50 years.”

Collier fears climate change will shift Africa’s competitive advantage in agriculture to Northern Eurasia and North America. Therefore, limited investment dollars must shift to cities which are more climate resilient. Byerlee disagrees.

“There is overwhelming and convincing evidence that agricultural growth is important for poverty reduction and food security,” said Byerlee. “Look at the Green Revolution in Asia and the institutional reforms in China in the early 1980s.”

The 2008 World Development Report also found GDP growth from agriculture benefits the income of the poor two to four times more than GDP growth from non-agriculture. So why isn’t this working for sub-Saharan Africa?

Byerlee points to Africa’s history of poor macroeconomic policies that have disadvantaged African farmers. Smallholder farmers have traditionally been taxed at high levels (as much as 50 percent 20 years ago before liberalization programs started kicking in). Rates have come down dramatically to 15-20 percent, but are still significantly higher than other countries.

“African states must level the playing field,” said Byerlee.

Government investment in public goods at four percent of agricultural GDP still lags behind that enjoyed by most other countries. That is less than half of what has been spent in Asia over the last couple of decades where investment in core public goods, R&D, rural roads, and irrigation have really made a difference.

Access to land and finance must also improve to support the growth of smallholder agribusiness. This especially includes secure, low cost, and transferrable land rights to allow efficient smallholders to expand.

Greater investment is also needed in technology and information. Research and development in Africa have been traditionally underfunded and understaffed. Despite involvement of agricultural research groups such as CGIAR over the last 40 years, only 35 percent of food crop area is planted to improved varieties. Smallholder farmers also often lack business development skills and access to primary education – a critical constraint to growth.

Reasons for optimism

Many of these macropolicies are slowing changing, and that makes Collier and Byerlee hopeful.

“After four decades in sub-Saharan Africa I feel optimistic about Africa’s food systems and future,” said Byerlee. “I see exciting opportunities in terms of market growth, private interest, and improved policies.”

Yields in Africa are low, but there is room for significant improvement. The continent is home to potentially 240 million hectares of uncultivated land and less then 20 percent of irrigation potential has been tapped.

African agricultural systems are transforming rapidly in response to rising rates of income growth, urbanization, and shifts in demand for high value and processed food, and feed for livestock. Higher food prices are incentivizing farmers to enter the market and increasing farmer income. Regional markets now accounting for only 5-10% of trade have much potential to expand, and Byerlee projects the value of African urban food markets to quadruple over the next 20 years.

Renewed investment in Africa is another reason for optimism. After decades of declining support donor agencies are refocusing their efforts on supporting agricultural development in Africa. Private sector investment, ranging from local to foreign investors, is also increasing. Collier spoke of the value pioneer commercial investors are bringing to unused and underutilized, but arable lands in Africa. These larger investors are better able to internalize the benefits of infrastructure supply while creating jobs and opening new markets.

The spur in foreign investment has drawn some fire from opponents worried about ‘land grabbing’. Collier and Byerlee both pointed out the need to differentiate between commercial investors and land speculators. The latter are being scrutinized, and for good reason.

Land speculators are leasing huge tracts of land over long time horizons and banking on the land’s option value if there is a big spike in food prices. This takes potentially arable land out of near-term production and out of the hands of local communities. Byerlee suggests governments impose controls on how rapidly the land is developed as one way of managing this problem.

What will a successful African food system look like in 2050?

"African peasantry as we know it today will not be preserved," projects Collier.

“If commercialization is successful most Africans will live in big coastal cities like the US and Europe,” said Collier. “Most of the remaining rural population will move to the hinterland of the big cities, because profitable agriculture will be selling into the big cities from close vicinity."

He envisions a mixture of different types of commercial agriculture ranging from consolidated family farms as is the norm in the US to large-scale enterprises as seen Brazil, but agriculture will not employ a lot of people. He sees an opportunity for commercial agriculture to piggyback off the infrastructure put in place by extractive natural resource companies.

Byerlee foresees Africa headed down a path similar to Thailand where a more egalitarian, smallholder commercial farmer model dominates (2-5 hectares). Large-scale farming has a legacy of failure in Africa, he said. He sees better prospects for large-scale irrigated rice and perhaps oil palm. Oil palm was actually an African crop prior to moving primarily to Malaysia and Indonesia. The value of South East Asian exports of palm oil is now greater than all agricultural exports from sub-Saharan Africa. In fact, Africa now imports $3.5 billion in palm oil.

“With billions of dollars at stake, big Asian companies are investing in Africa with the potential to create millions of jobs,” said Byerlee. “Oil palm could be a really big opportunity to transform African agriculture in the humid tropics, but state support is needed to facilitate inclusion of smallholders and safeguard social and environmental standards."

Africa has the natural resources to become a major player in the global agricultural export market and to bring down its alarmingly high malnutrition and poverty rates. What’s needed now is the political will, guidance, and investment to make that happen.

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