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The Effect on Healthcare Costs of Treating Comorbid Depressive Disorder with Chronic Disease

Objective: Does the cost of treating depressive disorder comorbidity inflate the cost of treating other chronic conditions?  The answer is important both to payers and to those organizing health care delivery.

Methods: Results from the national Medical Expenditure Panel Survey of 2015 (N≈30,000) provided the data. We estimated costs from medical records and from the self-reported utilization of healthcare. Using the Mental Health Component Summary score of the 12-Item Short Form we estimated the level of depression. We used a general linear model to estimate costs with fixed effects for chronic disease (present or absent) and depression (highest third, middle third, lowest third). Physical health/functional status served as a covariate. We analyzed each of eight different chronic conditions (arthritis, chronic obstructive pulmonary disease, high cholesterol, cancer, diabetes, stroke, coronary heart disease, and asthma) separately.

Results: In each of these analyses, the presence or absence of the chronic condition had a strong impact on cost. In addition, being at the highest level of depression also had a significant impact on cost. However, the interaction between depression and chronic disease diagnoses tended to account for only a small amount of variation in cost.

Conclusion: The combination of depression and chronic disease diagnosis did not have a strong synergistic effect on the cost of medical care. An additive model provides a more parsimonious explanation of data from this national sample.


Robert M. Kaplan, PhD

Clinical Excellence Research Center, Stanford University School of Medicine

Robert M. Kaplan, PhD is research director at CERC.  He has served as Chief Science Officer at the US Agency for Health Care Research and Quality (AHRQ) and Associate Director of the National Institutes of Health, where he led the behavioral and social sciences programs.  He is also a Distinguished Emeritus Professor of Health Services and Medicine at UCLA, where he led the UCLA/RAND AHRQ health services training program and the UCLA/RAND CDC Prevention Research Center. He was Chair of the Department of Health Services from 2004 to 2009.  From 1997 to 2004 he was Professor and Chair of the Department of Family and Preventive Medicine, at the University of California, San Diego. He is a past President of several organizations, including the American Psychological Association Division of Health Psychology, Section J of the American Association for the Advancement of Science (Pacific), the International Society for Quality of Life Research, the Society for Behavioral Medicine, and the Academy of Behavioral Medicine Research. Kaplan is a former Editor-in-Chief of Health Psychology and of the Annals of Behavioral Medicine.  His 20 books and over 500 articles or chapters have been cited more than 30,000 times and the ISI includes him in the listing of the most cited authors in his field (defined as above the 99.5th percentile).  Kaplan is an elected member of the National Academy of Medicine (formerly the Institute of Medicine).  Dr. Kaplan is currently Regenstrief Distinguished Fellow at Purdue University and Adjunct Professor of Medicine at Stanford University.


Lunch will be provided to those who RSVP.

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Moving Precision Medicine into Clinical Care and Health Policies: UCSF, Stanford, and Beyond

Precision medicine has evolved from a distant promise to reality, with many genomic tests now used in clinical care. Dr. Phillips will discuss the opportunities for researchers and clinicians to address the health policy implications of precision medicine, with a particular focus on opportunities at UCSF and Stanford. She will discuss a case study of a recent and highly controversial CMS national coverage decision on sequencing tests for cancer patients based on her article in JAMA 4/16/2018 (Phillips KA. Evolving Payer Coverage Policies on Genomic Sequencing Tests: Beginning of the End or End of the Beginning?)


Kathryn A. Phillips, PhD

Professor of Health Economics and Health Services Research and Founding Director, UCSF Center for Translational and Policy Research on Personalized Medicine University of California, San Francisco

Kathryn Phillips’s expertise is in the implementation of new technologies to improve healthcare. In 2007, she founded the UCSF Center for Translational and Policy Research on Personalized Medicine, which focuses on how to develop objective evidence on value and payer coverage of precision/personalized medicine. Dr. Phillips has published ~150 articles in major journals, including JAMA, New England Journal of Medicine, and Health Affairs, and has had continuous funding from the NIH as a Principal Investigator for 25 years. She serves on the editorial boards of the journals Health Affairs and Value in Health as well as all of the leading journals on precision medicine. A distinguishing characteristic of Dr. Phillips’ work is the translation of science into policy by bringing together perspectives across stakeholders. She has worked extensively with health plans, industry, and government agencies across the globe and has served on national and international scientific advisory committees for the National Academy of Medicine, Food and Drug Administration, and the President’s Council of Advisors on Science and Technology. Dr. Phillips is now serving on the Board of Directors for GenomeCanada (a non-profit organization that oversees and funds genomic research in Canada). In 2016, she was awarded a Rockefeller Foundation Bellagio Residency to pursue her work from a global perspective. Dr. Phillips holds degrees from UC-Berkeley, Harvard, and UT-Austin.


Lunch will be provided to those who RSVP.

Oksenberg Conference Room

Encina Hall

616 Serra Street

Stanford, CA 94305

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Organized by the Media & Democracy program at the Social Science Research Council, in collaboration with the Stanford Center on Philanthropy and Civil Society and the Center for Advanced Study in the Behavioral Sciences at Stanford University. 

The 2016 American elections intensified popular as well as scholarly interest in the relationship between media and democracy. The role of social media has featured particularly prominently in debates over fake news, information bubbles, and algorithmic propaganda. Increased scholarly interest is manifested in the numerous conferences that have been held over the last year or so, jointly exploring technological changes in the media, social interactions online, and their relationship to the quality of our democracy.  
 
Social Media and Democracy: Assessing the State of the Field and Identifying Unexplored Questions will convene researchers to take stock and look ahead. In a format of brief remarks and panel discussions, we seek to assess the current literature on social media and democracy together, and to set a research agenda for the field moving forward.  
 
Format: Each panelist will be asked to speak for up to ten minutes. In lieu of preparing traditional research presentations, we encourage attendees to reflect on the field as a whole, and ask themselves where they would like to see scholars go next. After hearing prepared remarks from panelists, each panel will have allotted time for a discussion with audience participation.
 
Panel-specific prompts are included below, geared toward key connecting themes: What gaps exist in current research? What studies would we like to see that do not exist right now? What do we not yet know about the impact of social media on democracy? What partnerships are needed to pursue research that can answer these questions?
 
 

Thursday, April 19   8:30-9:00am             Registration and Breakfast


 
9:00-9:30am
             Opening Remarks: Diana Mutz and Nate Persily  Overview of the Literature on Misinformation: Josh Tucker     
 
9:30-11:00am           Inflammatory Speech and Incivility Online
 
Panelists: Susan Benesch Bryan Gervais Diana Mutz Monica Stephens
 
Is social media a medium on which inflammatory speech and uncivil discourse are particularly prevalent? Online incivility may take a range of expressions, from unusually aggressive statements of individual political views to coordinated campaigns of harassment and intimidation. The targets may include out-partisans, professionals such as journalists, politicians, or government employees, and minority or underrepresented groups such as women and ethnic/religious minorities.
 
What, if anything, is different about inflammatory speech in the social media environment? What do we not yet understand about the origins, spread, and consequences of inflammatory speech online? Should we distinguish between different forms of incivility (e.g. direct threats vs. slurs, individual vs. coordinated harassment)? To what extent is online incivility related to real world actions (including, but not limited to, real world violence)?  
 
11:00-11:30am
      Coffee Break   
11:30am-1:00pm  Distribution and Effects of Fake News
 
Panelists: Renee DiResta Kelly Garrett David Rand Josh Tucker
 
The distribution of false information - intentional and unintentional - through social media has  become a significant source of anxiety in the media, politics, and public discourse. Exposure to false information can lead to mistaken impressions about the world, and may also deepen partisan divisions.  
 
What do we need to learn about how misinformation spreads online? We already have some research that quantifies exposure to misinformation online; what do we need to learn next about the effects of such exposure (on the individual level and in the aggregate)? Has the spread of social media raised new, unanswered questions about how people process information and classify it as true or false?  
 
1:00-2:00pm       Lunch   2:00-3:30pm            Correcting Disinformation
 
Panelists: Jonathan Albright Matthew Baum Adam J. Berinsky Matthew Gentzkow Emily Thorson
 
Once a person has been exposed to, and accepted as true, an inaccurate piece of information, how can the information be successfully corrected? What do we need to understand next about the possibilities and pitfalls for correcting misinformation?  
 
Do we have reason to suspect that social media changes the difficulty of correcting misperceptions? What do we not yet know about how corrections of factual information lead to changes in political attitudes or behavior? If we want to correct false beliefs, what do we need to learn about who should go about making corrections, and how?   
 
 
 
Friday, April 20th   8:30-9:00am  Breakfast
 
9:00am-10:30am
Homophily in the Social Media Sphere
 
Panelists: Damon Centola Annie Franco Shanto Iyengar Jaime Settle
 
Concern about online political discourse taking place in self-selected or algorithmically supported “information bubbles” is common, though there are differing views on how serious this problem is.  
 
Do we know whether social media is exceptional in enabling or limiting exposure to politically heterogeneous information? How do algorithms affect how much political content users see and/or the kind of political content to which they are exposed? What do we not yet understand about the frequency and consequences of political homophily on social media, as distinct from other types of media? What study would you like to see next on the prevalence and consequences of homogeneous political information? 

10:30-10:45am         Coffee Break   10:45am-12:15pm Globalization of the Marketplace of Ideas
 
Panelists: Nina Jankowicz Linda Kinstler Jennifer Pan


The use of social media for political ends is not limited to the United States, nor to traditional state actors. Narratives about politics are circulated online to influence domestic audiences, to drive political perceptions abroad, and to organize as well as suppress citizen unrest.
 
What do we need to learn next about the effectiveness of using social media to push the political interests of state- or non-state actors? What do we not yet understand about the dynamics at play when nation-states get involved in one another’s media ecosystems? How is this any different from when they previously did so using other media? What can we learn from studying the intersection of media and democracy in comparative perspective?
 
12:15-1:30pm Concluding Discussion Over Lunch (to-go available per request

Fisher Conference Center Frances C. Arillaga Alumni Center  Stanford University

Nate Persily James B. McClatchy, Professor of Law
Diane Mutz Samuel A. Stouffer Professor of Political Science and Communication, University of Pennsylvania
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Abstract:

In 2002 and 2003, Americans pointed to Japan after the Second World War as a model which proved that enemy countries could be remade into stable democratic allies through short military occupation. Planners and politicians drew on their understanding of events in Japan to learn "lessons" for a post-Saddam Iraq. In the years since, it has become common to blame the failures of intervention in Iraq on American ignorance and insufficient planning. But is that popular characterization correct? This talk discusses whether and how the planning phases for Japan and Iraq differed, and with what implications for the occupied countries.

 

Speaker Bio:

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dbarnes1
Dr. Dayna Barnes is a specialist in 20th century international history, American foreign policy, and East Asia. She is a visiting scholar at Stanford University's Center on Democracy, Development and Rule of Law, and assistant professor of history at City, University of London. Her book, Architects of Occupation: American Experts and the Planning for Postwar Japan, was published in Cornell University Press in March 2017.

Visiting Scholar at CDDRL
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Abstract:

The South African democratic process has crossed two significant milestones. One is political legitimacy in the sense that there is no significant threat to the constitution or political systems that the country adopted in 1996. Secondly, the systemic instability threat arising from the counter-revolutionary apartheid forces is now something of the past. There is simply no imminent threat of a retreat to the country’s authoritarian and racist past. The elusive goals remain in the economic arena – namely inclusive growth, widening inequality and slow development. How is the country shaping up to these challenges?

 

Speaker Bio:

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maphai
Professor Vincent Maphai an unusual and distinguished career in academia, private sector and public service. He is currently a visiting Professor at Williams College, Massachusetts, Center for Global Studies. In an academic career spanning two decades, he studied and taught at various universities both locally. He was professor extraordinaire in the Department of Political Science at the University of South Africa (UNISA).. who held fellowships at Harvard (1988), Princeton (1989) and Stanford (1995). From 1991 to 1994 he was associate professor and head of the political science department at the University of the Western Cape. He also served as a Research Executive Director of social dynamics at the HSRC for three years..

Vincent Maphai Visiting Professor at Williams College
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Speaker Bio:

Beatriz Magaloni Beatriz Magaloni
Beatriz Magaloni is an Associate Professor in the Department of Political Science and a Senior Fellow at the Freeman Spogli Institute for International Studies (FSI) at Stanford University. She is also an affiliated faculty member of the Woods Institute of the Environment (2011-2013) and a Faculty Fellow at the Stanford Center for International Development. Her first book, Voting for Autocracy: Hegemonic Party Survival and its Demise in Mexico (Cambridge University Press, 2006), won the Best Book Award from the Comparative Democratization Section of the American Political Science Association and the 2007 Leon Epstein Award for the Best Book published in the previous two years in the area of political parties and organizations. Her second book, Strategies of Vote Buying: Democracy, Clientelism, and Poverty Relief in Mexico (co-authored with Alberto Diaz Cayeros and Federico Estévez), studies the politics of poverty relief. Why clientelism is such a prevalent form of electoral exchange, how it distorts policies aimed at aiding the poor, and when it can be superseded by more democratic and accountable forms of electoral exchange are some of the central questions that the book addresses.

Dept. of Political Science
Encina Hall, Room 436
Stanford University,
Stanford, CA

(650) 724-5949
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Senior Fellow at the Freeman Spogli Institute for International Studies
Graham H. Stuart Professor of International Relations
Professor of Political Science
beatriz_magaloni_2024.jpg MA, PhD

Beatriz Magaloni Magaloni is the Graham Stuart Professor of International Relations at the Department of Political Science. Magaloni is also a Senior Fellow at the Freeman Spogli Institute, where she holds affiliations with the Center on Democracy, Development and the Rule of Law (CDDRL) and the Center for International Security and Cooperation (CISAC). She is also a Stanford’s King Center for Global Development faculty affiliate. Magaloni has taught at Stanford University for over two decades.

She leads the Poverty, Violence, and Governance Lab (Povgov). Founded by Magaloni in 2010, Povgov is one of Stanford University’s leading impact-driven knowledge production laboratories in the social sciences. Under her leadership, Povgov has innovated and advanced a host of cutting-edge research agendas to reduce violence and poverty and promote peace, security, and human rights.

Magaloni’s work has contributed to the study of authoritarian politics, poverty alleviation, indigenous governance, and, more recently, violence, crime, security institutions, and human rights. Her first book, Voting for Autocracy: Hegemonic Party Survival and its Demise in Mexico (Cambridge University Press, 2006) is widely recognized as a seminal study in the field of comparative politics. It received the 2007 Leon Epstein Award for the Best Book published in the previous two years in the area of political parties and organizations, as well as the Best Book Award from the American Political Science Association’s Comparative Democratization Section. Her second book The Politics of Poverty Relief: Strategies of Vote Buying and Social Policies in Mexico (with Alberto Diaz-Cayeros and Federico Estevez) (Cambridge University Press, 2016) explores how politics shapes poverty alleviation.

Magaloni’s work was published in leading journals, including the American Political Science Review, American Journal of Political Science, Criminology & Public Policy, World Development, Comparative Political Studies, Annual Review of Political Science, Cambridge Journal of Evidence-Based Policing, Latin American Research Review, and others.

Magaloni received wide international acclaim for identifying innovative solutions for salient societal problems through impact-driven research. In 2023, she was named winner of the world-renowned Stockholm Prize in Criminology, considered an equivalent of the Nobel Prize in the field of criminology. The award recognized her extensive research on crime, policing, and human rights in Mexico and Brazil. Magaloni’s research production in this area was also recognized by the American Political Science Association, which named her recipient of the 2021 Heinz I. Eulau Award for the best article published in the American Political Science Review, the leading journal in the discipline.

She received her Ph.D. in political science from Duke University and holds a law degree from the Instituto Tecnológico Autónomo de México.

Director, Poverty, Violence, and Governance Lab
Co-director, Democracy Action Lab
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Associate Professor in the Department of Political Science and a Senior Fellow at the Freeman Spogli Institute for International Studies (FSI) at Stanford University
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Abstract:

Financial markets expose individuals to the broader economy. Does participation in fi nancial markets also lead individuals to re-evaluate the costs of conflict, their views on politics and even their votes? Prior to the 2015 Israeli elections, we randomly assigned fi nancial assets from Israeli and Palestinian companies to likely voters and gave them incentives to actively trade for up to seven weeks. Opportunities to trade in fi nancial markets systematically shifted vote choices and increased support for peace initiatives. These effects persist a year after the experiment, and appear consistent with fi nancial market exposure leading to increased awareness of the economic risks of conflict.

 

Speaker Bio:

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saumitra jha
Along with being a Senior Fellow at FSI, Saumitra Jha is an Associate Professor of Political Economy at the Stanford Graduate School of Business, by courtesy, of Economics and of Political Science, and a Senior Fellow at SIEPR. Saum holds a BA from Williams College, master’s degrees in economics and mathematics from the University of Cambridge, and a PhD in economics from Stanford University. Prior to returning to Stanford, he was an Academy Scholar at Harvard University. Saum has been a Fellow of the Niehaus Center for Globalization and Governance and the Center for the Study of Democratic Politics at Princeton University and received the Michael Wallerstein Award for best published article in Political Economy from the American Political Science Association in 2014 for his research on ethnic tolerance. Saumitra has consulted on economic and political risk issues for the United Nations/ WTO, the World Bank and other organizations. Having grown up in England, Scotland and the Indian Himalaya, Saum's research interests now take him to Israel, Japan, Mexico and elsewhere.

Saumitra Jha Associate Professor of Political Economy at Stanford’s Graduate School of Business
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Modern-day markets do not arise spontaneously or evolve naturally. Rather they are crafted by individuals, firms, and most of all, by governments. Thus "marketcraft" represents a core function of government comparable to statecraft and requires considerable artistry to govern markets effectively. Just as real-world statecraft can be masterful or muddled, so it is with marketcraft. 

In his new book, Steven Vogel builds his argument upon the recognition that all markets are crafted then systematically explores the implications for analysis and policy. In modern societies, there is no such thing as a free market. Markets are institutions, and contemporary markets are all heavily regulated. The "free market revolution" that began in the 1980s did not see a deregulation of markets, but rather a re-regulation. Vogel looks at a wide range of policy issues to support this concept, focusing in particular on the US and Japan. He examines how the US, the "freest" market economy, is actually among the most heavily regulated advanced economies, while Japan's effort to liberalize its economy counterintuitively expanded the government's role in practice. 

Marketcraft demonstrates that market institutions need government to function, and in increasingly complex economies, governance itself must feature equally complex policy tools if it is to meet the task. In our era-and despite what anti-government ideologues contend-governmental officials, regardless of party affiliation, should be trained in marketcraft just as much as in statecraft.

SPEAKER

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Steven K. Vogel, Il Han New Professor of Asian Studies and a Professor of Political Science at the University of California, Berkeley

BIO

Steven K. Vogel is the Il Han New Professor of Asian Studies and a Professor of Political Science at the University of California, Berkeley. He specializes in the political economy of the advanced industrialized nations, especially Japan. He recently completed a book, entitled Marketcraft: How Governments Make Markets Work (Oxford, 2018), which argues that markets do not arise spontaneously but rather are crafted by individuals, firms, and most of all by governments.  Thus “marketcraft” represents a core function of government comparable to statecraft.  The book systematically reviews the implications of this argument, critiquing prevalent schools of thought and presenting lessons for policy.  Vogel is also the author of Japan Remodeled: How Government and Industry Are Reforming Japanese Capitalism (Cornell, 2006) and co-editor (with Naazneen Barma) of The Political Economy Reader: Markets as Institutions (Routledge, 2008). His first book, Freer Markets, More Rules: Regulatory Reform in Advanced Industrial Countries  (Cornell, 1996), won the Masayoshi Ohira Memorial Prize. He edited his mother’s book, Suzanne Hall Vogel, The Japanese Family in Transition: From the Professional Housewife Ideal to the Dilemmas of Choice(Rowman & Littlefield, 2013), and a volume on U.S.-Japan Relations in a Changing World(Brookings, 2002).  He won the Northern California Association of Phi Beta Kappa Teaching Excellence Award in 2002, and the UC Berkeley Faculty Award for Outstanding Mentorship of Graduate Student Instructors in 2005.  He has been a columnist for Newsweek-Japan and the Asahi Shimbun, and he has written extensively for the popular press.  He has worked as a reporter for the Japan Times in Tokyo and as a freelance journalist in France. He has taught previously at the University of California, Irvine and Harvard University. He has a B.A. from Princeton University and a Ph.D. in Political Science from the University of California, Berkeley.

Steven K. Vogel, Il Han New Professor of Asian Studies and a Professor of Political Science at the University of California, Berkeley
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As millions marched against gun violence across the country on Saturday, research by Stanford Health Policy experts about the impact of gun ownership on public health was also in the spotlight.

The Washington Post published an in-depth story about how the work of gun researchers is finally getting attention — an unfortunate consequence of the recent mass shootings in the United States.

David Studdert — a professor of medicine and law — and Yifan Zhang, a biostatics and data analyst with Stanford Health Policy, along with seasoned gun researcher Garen Wintemute of UC Davis’s Violence Prevention Research Program, are trying to answer the question: Are you more or less likely to die if you own a firearm?

“The explosion of national interest in the problem of gun violence since the Parkland shooting has been remarkable,” said Studdert, who is also a core faculty member at Stanford Health Policy.  “And it is inspiring to hear students’ voices — that is definitely a new twist in the politics around this issue. I think there is momentum for change, but I remain pessimistic that we will see the enactment of any substantial reforms at the federal level.”

The Post wrote:

Studdert’s group is using a data set unique to California because of the state’s strict gun laws. Every time a gun is sold in California, a background check logs the purchase and purchaser with California authorities, who also have been unique in their willingness to share such politically fraught data with academic researchers.

 

Using a sample of 25 million people (taken from California’s voter registration records), Studdert’s team plans to identify handgun owners with the firearm sales records, then compare that against state death records.

 

The resulting data in theory will help them determine the relationship — whether good or bad — between gun ownership and death.

 

They call the project LongSHOT, a nod to the project’s scale and ambition.

 

Academic researchers who were studying the impact of gun violence on public health were dealt a huge financial and political blow in 1996, when the so-called Dickey Amendment was passed by Congress under pressure from gun lobbyists. The law forbids the Centers for Disease Control and Prevention to fund research that might be seen as advocating for gun control. This choked off federal grant money and essential data-gathering on gun violence.

But tucked into the government spending bill in Congress last week was language that indicates the CDC now has the authority to conduct research on the causes and effects of gun violence. Though gun researchers are skeptical that the change in tone will lead to any significant support or funding, some believe that it’s a start. The $1.3 trillion government funding measure also includes efforts to improve state compliance with the national background check system, as well as funding for school counseling and safety programs.

Again, from The Post story:

Yifan Zhang was finishing her PhD in biostatistics at Harvard five years ago when news broke of the Sandy Hook Elementary School shooting.

 

As a graduate student from China, specializing in highly technical design of clinical drug trials, she had little connection to America’s long-running debate over gun violence. But even now, she said, the anguished faces of those parents she saw on television remain seared in her memory.

 

So when she heard about a gun-violence research project at Stanford University that could use the statistical skills she had honed on pharmaceuticals, she jumped at the chance.

 

“I have a son who just turned 1,” said Zhang, 31. “When I think about what I will need to teach him about protecting himself, I think about that school shooting.”

 

Zhang hopes the Stanford team can one day have an impact.

“I think there are going to be some big decisions that the whole country has to make together, and I’m hoping that our research can help provide evidence and information for the decision making,” she said.

 

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Wednesday, April 18, 2018

1:30 – 2:30pm

Encina Hall, Philippines Room

FSI and the Ford Dorsey IPS program will be hosting Mercy Corps as they visit campus to speak about their Global Internship Program.

The Mercy Corps Global Internship Program offers exploration into future careers in international relief and development while supporting our beneficiaries in their local communities in 25 countries around the world. Their internships revolve around a particularly demanding mission - to help people on the ground turn the crises they confront into the opportunities they deserve. Driven by local needs, our programs provide communities in the world’s most challenging places with the tools and support they need to transform their lives.

Mercy Corps is an international relief and development organization working in over 40 countries worldwide helping people build secure, productive and just communities. From poverty and malnutrition to natural disasters and global warming, Mercy Corps sees an opportunity to create transformative change. In crisis, we believe in the power of human potential. Mercy Corps connects people to the resources they need to build better, stronger lives.

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