The U.S. Preventive Services Task Force recommends adults between the ages of 40 and 75 take a cholesterol-lowering statin drug to help prevent heart attacks and strokes if they are at risk of cardiovascular disease.

One in three Americans die of heart attacks or strokes. And those with no signs or symptoms, as well as no past history of cardiovascular disease, can still be at risk.

The independent panel of medical experts from around the nation said in a news release that statins could help those who have a risk factor for cardiovascular disease — such as high cholesterol or blood pressure, diabetes or those who smoke — and have at least a 7.5 percent risk of having a cardiovascular event in the next 10 years.

The task force also called for more research on the use of prescribing statins for children and adolescents who are at risk of heart disease.

The American Heart Association and American College of Cardiology have been recommending statins in adults for several years. The task force is now making a similar recommendation for primary prevention based on the latest clinical trials and research.

“The task force looked carefully at current data to identify who can benefit the most from taking statins,” said task force chair Albert L. Siu, MD, MSPH, who is also chair of the Ellen and Howard C. Katz Mount Sinai Health System.

“People with no signs, symptoms, or history of cardiovascular disease can still be at risk of heart attack or stroke,” said task force member Douglas K. Owens, MD, a Stanford professor of medicine and director of the Center for Health Policy and Center for Primary Care and Outcomes Research at Stanford Health Policy.

“Fortunately, for certain people at increased risk, statins can be very effective at preventing these events,” said Owens, who emphasizes that adults who fall into those risk and age groups must first consult with their physicians.

The task force said all adults could reduce their risk of cardiovascular disease by not smoking, eating a healthy diet, engaging in physical activity and limiting alcohol use. Managing high blood pressure and high cholesterol and taking aspirin when indicated can also help prevent heart attacks and strokes.

Based on the current evidence, the task force said, it is not yet clear whether taking statins is beneficial for people who are older than 75. But they did find the effectiveness of statins is the same for both men and women.

This is the first time the task force has changed its fundamental approach since 2008, when it recommended screening for abnormal amount of lipids in the blood. While screening remains key, most adults are now routinely screened as part of an overall cardiovascular risk assessment.

Therefore, the task force found the more relevant clinical question is no longer whom to screen for elevated cholesterol, but rather whom to treat with preventive medication once increased cardiovascular risk has been identified in an individual.

The Preventive Services Task Force also announced that there is not enough data and evidence to assess the balance of benefits and harms in screening for high cholesterol in children and adolescents up to age 20.

While some experts have recommended lipid screening in children and teens, the task force found that the evidence shows it’s difficult to predict which children who have high cholesterol will continue to have it as they age.

“There is currently not enough research to determine whether screening all average-risk children and adolescents without symptoms leads to better cardiovascular health in adulthood.” said Task Force Vice Chair David C. Grossman, MD, MPH. “In addition, the potential harms of long-term use of cholesterol-lowering medication by children and adolescents are not yet understood.”

The public can review the findings and comment on the task force website.

Other articles on the recommendation include:

The Associated Press

MedPage Today

Reuters

HealthDay

When I first started the Stanford e-Japan program, I never expected to be up on that podium making a speech [at Stanford University]… Yet there I stood, a little more grown up than before.
—Seiji Wakabayashi, Kumon Kokusai Junior-Senior High School

If I hadn’t participated in this program, I wouldn’t have been as interested in the U.S. as I am right now.
—Hikaru Suzuki, Senior High School at Otsuka, University of Tsukuba

I am very grateful to be given the chance to think about and to discuss with my fellow classmates what we should do in order to strengthen the U.S.–Japan relationship in the future.
—Haruki Kitagawa, Keio Senior High School

The Stanford Program on International and Cross-Cultural Education (SPICE) honored three of the top students of the inaugural 2015 Stanford e-Japan distance-learning course at an event at Stanford University on November 2, 2015. The three Stanford e-Japan Day honorees—Haruki Kitagawa (Keio Senior High School), Hikaru Suzuki (Senior High School at Otsuka, University of Tsukuba), and Seiji Wakabayashi (Kumon Kokusai Junior-Senior High School)—were recognized for their coursework and exceptional research essays that focused respectively on “A Comparison and Analysis of Educational Systems: What Is ‘Successful’ Education?,” “Why the Japanese Have a Good Image of America,” and “Schooling Japan.”

Stanford e-Japan Day featured welcoming comments by Dr. Gary Mukai, SPICE Director, and opening remarks on youth and the future of U.S.–Japan relations by Deputy Consul General Nobuhiro Watanabe, Consulate General of Japan in San Francisco. Deputy Consul General Watanabe reinforced that youth are the ones to shoulder the U.S.–Japan relationship in the coming years, and that he is very much looking forward to the day when these students will engage in furthering our two countries’ strong ties.

Waka Takahashi Brown, Stanford e-Japan Instructor, gave an overview of the course. Stanford e-Japan is a distance-learning course on U.S. society and culture and U.S.–Japan relations that is offered annually to 25–30 high school students across Japan. The course presents a creative and innovative approach to teaching high school students about U.S. society and culture and U.S–Japan relations, and provides Japanese students with unique opportunities to interact with diplomats and top scholars affiliated with Stanford University and other institutions through online lectures and discussions. Importantly, the course introduces both American and Japanese perspectives on many historical and contemporary issues.

Each student honoree gave a succinct and lucid summary of his/her research essay and skillfully answered questions from the audience. Following the question-and-answer period, each student was presented with a plaque by Brown. Following the presentations, the students and their families joined the audience in a luncheon.

Following the event, Stanford undergraduate Mathieu Rolfo took time from his studies to take the three honorees on a tour of the Stanford campus. Mathieu is a former student in SPICE’s Reischauer Scholars Program (RSP), a distance-learning course on Japan and U.S.–Japan relations that has been offered to high school students in the United States for 12 years. RSP Instructor Naomi Funahashi honored Rolfo as one of her top three RSP students in 2011. Funahashi and Brown are planning to continue to engage their students “virtually” across the Pacific.

Stanford e-Japan has been generously funded for the first three years (2015–17) by a grant from the United States-Japan Foundation. SPICE supporter Amanda Minami Chao was in attendance and had the chance to share her thoughts on Brown University with student honoree Seiji Wakabayashi who plans to apply to her alma mater.

During a recent trip to Japan, Mukai had the opportunity to meet with other excellent students who were enrolled in the inaugural course. Shoko Kitamura, Waseda Honjo Senior High School, noted that she especially enjoyed a lecture by Dr. Joseph Yasutake on Japanese-American internment during which Yasutake shared his first-hand accounts. Tairi Goto, International School of Asia in Karuizawa, stated that he especially appreciated a class activity during which he was introduced to textbook descriptions of the atomic bombing of Japan from Taiwan, Korea, Japan, China, and the United States. Misaki Katayama, Hiroshima Prefectural Hiroshima Junior/Senior High School, commented on her interest in learning about Japanese picture brides who left prefectures like Hiroshima to the United States in the early 20th century.

Reflecting back on the inaugural Stanford e-Japan course and e-Japan Day, Brown noted, “The inaugural group of e-Japan students was phenomenal. It was wonderful to be able to meet at least some of the students in person on e-Japan Day, although I felt like I had already met them through our interaction during the course. I have no doubt that future leaders, diplomats, and entrepreneurs will emerge from this cohort. ”

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