Public Health
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Title: Research in Progress: Doug Owens - Development of the New USPSTF Guidelines on Screening for Lung Cancer and Colorectal Cancer

Brief Abstract: 

Discuss the development of the two new draft guidelines from the U.S. Preventive Services Task Force.  Screening for lung cancer and colorectal cancer are two of the most complex and important cancer screening guidelines in the USPSTF portfolio.  Describing the methods the USPSTF uses, including the evidence reviews and modeling that helped us create these new recommendations.

 

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Encina Commons, Room 201 
615 Crothers Way Stanford, CA 94305-6006 

Executive Assistant: Soomin Li, soominli@stanford.edu
Phone: (650) 725-9911

(650) 723-0933 (650) 723-1919
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Henry J. Kaiser, Jr. Professor
Professor, Health Policy
Senior Fellow, Freeman Spogli Institute for International Studies
Professor, Management Science & Engineering (by courtesy)
doug-headshot_tight.jpeg MD, MS

Douglas K. Owens is the Henry J. Kaiser, Jr. Professor, Chair of the Department of Health Policy in the Stanford University School of Medicine and Director of the Center for Health Policy (CHP) in the Freeman Spogli Institute for International Studies (FSI). He is a general internist, a Professor of Management Science and Engineering (by courtesy), at Stanford University; and a Senior Fellow at the Freeman Spogli Institute for International Studies.

Owens' research includes the application of decision theory to clinical and health policy problems; clinical decision making; methods for developing clinical guidelines; decision support; comparative effectiveness; modeling substance use and infectious diseases; cardiovascular disease; patient-centered decision making; assessing the value of health care services, including cost-effectiveness analysis; quality of care; and evidence synthesis.

Owens chaired the Clinical Guidelines Committee of the American College of Physicians for four years. The guideline committee develops clinical guidelines that are used widely and are published regularly in the Annals of Internal Medicine. He was a member and then Vice-Chair and Chair of the U.S. Preventive Services Task Force, which develops national guidelines on preventive care, including guidelines for screening for breast, colorectal, prostate, and lung cancer. He has helped lead the development of more than 50 national guidelines on treatment and prevention. He also was a member of the Second Panel on Cost Effectiveness in Health and Medicine, which developed guidelines for the conduct of cost-effectiveness analyses.

Owens also directed the Stanford-UCSF Evidence-based Practice Center. He co-directs the Stanford Health Services Research Program, and previously directed the VA Physician Fellowship in Health Services Research, and the VA Postdoctoral Informatics Fellowship Program.

Owens received a BS and an MS from Stanford University, and an MD from the University of California-San Francisco. He completed a residency in internal medicine at the University of Pennsylvania and a fellowship in health research and policy at Stanford. Owens is a past-President of the Society for Medical Decision Making. He received the VA Undersecretary’s Award for Outstanding Achievement in Health Services Research, and the Eisenberg Award for Leadership in Medical Decision Making from the Society for Medical Decision Making. Owens also received a MERIT award from the National Institutes on Drug Abuse to study HIV, HCV, and the opioid epidemic. He was elected to the American Society for Clinical Investigation (ASCI) and the Association of American Physicians (AAP.)

Chair, Department of Health Policy, School of Medicine
Director, Center for Health Policy, Freeman Spogli Institute for International Studies
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News
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Researchers have long known that the number of human infections from the bat-borne Nipah virus fluctuates from year to year. Now, a new study provides insights into the reasons why.

In a Stanford News Q&A, Stanford epidemiologist Stephen Luby, MD, discussed the findings and how they relate to SARS-CoV-2, the virus that causes COVID-19.

Read the rest at Scope

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Two bats hanging upside down Charles J. Sharp of Sharp Photography / Wikimedia
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Researchers have long known that the number of human infections from the bat-borne Nipah virus fluctuates from year to year. A new study provides insights into the reasons why. Stanford epidemiologist Stephen Luby, MD, discussed the findings and how they relate to COVID-19.

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With vaccines against SARS-CoV-2, the virus that causes Covid-19, on the near-term horizon, U.S. policymakers are focusing on how to ensure that Americans get vaccinated. This challenge has been compounded by reports that White House officials are exerting undue influence over the agencies that would ordinarily lead such efforts, the Food and Drug Administration and the Centers for Disease Control and Prevention.

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Commentary
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STAT News
Authors
Michelle Mello
Number
2020
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News Type
News
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Water sensitive cities show how holistic approaches can counter the health and wellbeing problems associated with urban dryness. About 1.6 billion people live in countries with water scarcity, and this number is projected to double in two decades.

Read the rest at  BMJ

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Dry town Burak Kara / Stringer/ GettyImages
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Water sensitive cities show how holistic approaches can counter the health and wellbeing problems associated with urban dryness. About 1.6 billion people live in countries with water scarcity, and this number is projected to double in two decades.

Authors
Stephen P. Luby
News Type
Q&As
Date
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A little known virus may have a lot to teach us about dealing with COVID-19. Discovered 20 years ago, Nipah virus can spread from bats or pigs to humans. Found only in South and South East Asia so far, it kills nearly three-quarters of the people it infects. There is no vaccine for it and no cure, and it has many strains capable of spreading from person to person, increasing the chances of a strain emerging with the ability to rapidly spread beyond the region.

Read the rest at  Stanford News

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Bat hanging from a branch Jakub Hałun / Wikimedia Commons
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Stanford epidemiologist Stephen Luby discusses surprising results of a recent study on Nipah virus, a disease with no vaccine and a mortality rate of up to 70 percent.

Authors
David Relman
News Type
Commentary
Date
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We find ourselves ten months into one of the most catastrophic global health events of our lifetime and, disturbingly, we still do not know how it began. What’s even more troubling is that despite the critical importance of this question, efforts to investigate the origins of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and of the associated disease, coronavirus disease 2019 (COVID-19), have become mired in politics, poorly supported assumptions and assertions, and incomplete information.

Read the rest at Proceedings of the National Academy of Sciences

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People in suits burying a body Shutterstock/PradeepGaurs
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We find ourselves ten months into one of the most catastrophic global health events of our lifetime and we still do not know how it began. Despite the critical importance of this question, efforts to investigate the origins have become mired in politics, poorly supported assumptions and assertions, and incomplete information.

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Few issues in the policy response to the coronavirus disease 2019 (COVID-19) pandemic have inspired as impassioned debate as school reopening. There is broad agreement that school closures involve heavy burdens on students, parents, and the economy, with profound equity implications, but also that the risk of outbreaks cannot be eliminated even in a partial reopening scenario with in-school precautions. Consensus largely ends there, however: the approaches states and localities have taken to integrating these concerns into school reopening plans are highly variable.

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Journal Articles
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Journal Publisher
JAMA Network
Authors
Jeremy Goldhaber-Fiebert
David Studdert
Michelle Mello
Number
2020
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On August 17, 2020, the Los Angeles Unified School District launched a program to test more than 700,000 students and staff for SARS-CoV-2. The district is paying a private contractor to provide next-day, early-morning results for as many as 40,000 tests daily. As of October 4, a total of 34,833 people had been tested at 42 sites. The program is notable not only because it’s ambitious, but also because it’s unusual: testing is conspicuously absent from school reopening plans in many other districts. Typically, exhaustive attention has instead focused on physical distancing, face coverings, hygiene, staggering of schedules, and cohorting (dividing students into small, fixed groups). Although the Centers for Disease Control and Prevention (CDC), the American Academy of Pediatrics, the National Academies of Sciences, Engineering, and Medicine, and state officials have urged schools to prepare for Covid-19 cases, they have offered strikingly little substantive guidance on testing. Immediate attention to improving testing access and response planning is essential to the successful reopening of schools.

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Publication Type
Journal Articles
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Journal Publisher
New England Journal of Medicine
Authors
Michelle Mello
Number
2020
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Abstract

The economic and mortality impacts of the COVID-19 pandemic have been widely discussed, but there is limited evidence on their relationship across demographic and geographic groups. We use publicly available monthly data from January 2011 through April 2020 on all-cause death counts from the Centers for Disease Control and Prevention and employment from the Current Population Survey to estimate excess all-cause mortality and employment displacement in April 2020 in the United States. We report results nationally and separately by state and by age group. Nationally, excess all-cause mortality was 2.4 per 10,000 individuals (about 30% higher than reported COVID deaths in April) and employment displacement was 9.9 per 100 individuals. Across age groups 25 y and older, excess mortality was negatively correlated with economic damage; excess mortality was largest among the oldest (individuals 85 y and over: 39.0 per 10,000), while employment displacement was largest among the youngest (individuals 25 to 44 y: 11.6 per 100 individuals). Across states, employment displacement was positively correlated with excess mortality (correlation = 0.29). However, mortality was highly concentrated geographically, with the top two states (New York and New Jersey) each experiencing over 10 excess deaths per 10,000 and accounting for about half of national excess mortality. By contrast, employment displacement was more geographically spread, with the states with the largest point estimates (Nevada and Michigan) each experiencing over 16 percentage points employment displacement but accounting for only 7% of the national displacement. These results suggest that policy responses may differentially affect generations and geographies.

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Publication Type
Journal Articles
Publication Date
Journal Publisher
Proceedings of the National Academy of Sciences
Authors
Maria Polyakova
Number
2020
Paragraphs

When an experienced provider opts to leave a healthcare workforce (attrition), there are significant costs, both direct and indirect. Turnover of healthcare providers is underreported and understudied, despite evidence that it negatively impacts care delivery and negatively impacts working conditions for remaining providers. In the Veterans Affairs (VA) healthcare system, attrition of women’s health primary care providers (WH-PCPs) threatens a specially trained workforce; it is unknown what factors contribute to, or protect against, their attrition.

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Publication Type
Journal Articles
Publication Date
Journal Publisher
Journal of General Internal Medicine
Authors
Number
2020
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