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Recent experimental evidence finds that the decision maker in a collective decision making entity with proposal power attracts a disproportionate amount of the blame or reward by those materially affected by these decisions. In the case of coalition governments evidence suggests that voters have heuristics for assigning responsibility for economic outcomes to individual parties and that they tend to disproportionately direct the economic vote toward the Prime Minister party. This essay demonstrates that voters also identify the Finance Minister party as an agenda setter on economic issues depending on whether the coalition context exaggerates or mutes its perceived agenda power. We define cabinet context as the extent to which coalition parties take issue ownership for particular policy areas. We find that when decision making is compartmentalized, voters perceive the finance minister as having agenda power and hence it receives a relatively larger economic vote; in more “diffuse” cabinet contexts it is the PM Party that is attributed responsibility for the economy.

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Ray Duch

Raymond Duch is an Official Fellow at Nuffield College, University of Oxford, and the Director of the Nuffield Centre for Experimental Social Sciences (CESS), which currently has centres in Oxford (UK), Santiago (Chile), Tianjin (China) and Pune (India). Prior to assuming these positions, he was the Senator Don Henderson Scholar in Political Science at the University of Houston. He received his BA (Honours) from the University of Manitoba in Canada and his MA and PhD from the University of Rochester. In addition, he has held visiting appointments at the Universitat Pompeu Fabra, Barcelona; the Hoover Institute and the Graduate School of Management, Stanford University; the Institute for Social Research Oslo; the Université de Montréal; and the Wissenschaftszentrum Berlin für Sozialforschung. He is currently the Long Term Visiting Professor at the Institute for Advanced Studies at the Toulouse School of Economics.

He draws on theory, experiments and public opinion analysis to understand how citizens solve decision-making challenges. This includes looking at how citizens use information shortcuts to make decisions. For example in ‘Context and Economic Expectations: When Do Voters get it Right?’ (British Journal of Political Science, 2010), he demonstrates how information shortcuts result in quite accurate expectations regarding price fluctuations in 12 European countries. One of his current areas of interest is the micro-foundations of cheating and unethical behaviour. He has run real effort tax compliance experiments designed to understand who cheats at taxes, the results of which are summarized in ‘Why We Cheat?’ (currently under review). An extension of this project examines tax compliance in different tax regimes.

Ray has served as Associate Editor of the American Journal of Political Science and the Journal of Experimental Political Science. He is one of the founders of the European Political Science Association and the International Meeting on Behavioural Science (IMESBESS), and he is currently Vice President of the Midwest Political Science Association. In 2015, Ray was selected as a member of the UK Cabinet Office Cross-Whitehall Trial Advice Panel to offer Whitehall departments technical support in designing and implementing controlled experiments to assess policy effectiveness. He was recently nominated to the Evidence in Governance and Politics network.

This event is co-sponsored by the Hoover Institution.

 

Raymond Duch speaker Nuffield College, University of Oxford
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Donald L. Lucas Endowed Professor in Economics
Professor of Economics
Senior Fellow at the Stanford Institute for Economic Policy Research
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Kyle Bagwell is the Donald L. Lucas Endowed Professor in Economics at Stanford University. He is also a Senior Fellow of the Stanford Institute for Economic Policy Research, a Research Associate of the National Bureau of Economic Research and a Faculty Affiliate of the Stanford Center on Global Poverty and Development.

Bagwell works in the fields of International Trade, Industrial Organization and Game Theory. His research examines a range of theoretical and empirical questions relating to the purpose and design of GATT/WTO. He also explores theories of competition and cooperation in settings where asymmetric information is present. His research has been published in numerous academic journals, and in a book, The Economics of the World Trading System, co-authored with Robert W. Staiger and published by The MIT Press (2002).

Bagwell holds undergraduate degrees in Economics and Mathematics from SMU (1983) and a Ph.D. in Economics from Stanford University (1986). Prior to joining Stanford at the start of 2009, he was a faculty member at Northwestern University (1986-96) and at Columbia University (1996-2008). He was the Kelvin J. Lancaster Professor of Economic Theory at Columbia (2000-08).

Bagwell has served on the editorial boards of numerous academic journals, and he was an Editor at The Rand Journal of Economics (1996-2002). He was a National Fellow of the Hoover Institution (1991-92) and a Fellow at CASBS at Stanford (2014-15). He was the Director of the Stanford Institute for Theoretical Economics (2010-13), and a Reporter for the American Law Institute in its study of Principles of Trade Law: The World Trade Organization (2002-12). He is also a Fellow of the Econometric Society (2005).

 

 

Affiliated faculty at The Europe Center
Affiliated faculty at the Stanford Center on Global Poverty and Development
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Abstract:

Ever since the Millennium Message, Putin's first presidential speech on January 1, 2000, the Kremlin's political architects have cultivated a narrative of Russia as a unique nation on a righteous path toward restored greatness. The process of myth-making is intertwined with the policies involved in remaking Russia as a global power, as the regime builds legitimacy through careful messaging on Russian nationhood, history, morality, and geopolitical strength, using law and policy to embed those concepts as institutions and persuade citizens that Russia needs autocracy to survive. This talk traces the Kremlin's cooptation of culture and history to tell a certain story about Russia and its citizens, and examines public opinion polls to assess the degree to which the strategy is working, as well as street protests and radical performance art that attempts to claim spaces of agency for citizens who don't fit into the mythic mold.

 

 

Speaker Bio:

 

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alice underwood
Alice E.M. Underwood is a Pre-Doctoral Fellow at the Center on Democracy, Development, and the Rule of Law and a Ph.D. Candidate in the Department of Comparative Literature at Stanford University. She is a Weiland Fellow at Stanford and a former Title VIII Fellow at the Kennan Institute at the Woodrow Wilson International Center for Scholars, and has published with Intersection, The Russia File, Russian Life, and Harvard International Review.

 
Pre-doctoral fellow at the Center on Democracy, Development, and the Rule of Law.
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Matteo Renzi, former Prime Minister of Italy


Matteo Renzi was born in Florence in January 1975. In 2004 he was elected president of the province of Florence; five years later, in 2009, he was elected Mayor of Florence. In 2012 he ran in the primary elections for the centre-left, losing in the run-off. In 2013 he stood once again in the primaries, this time for leader of the Italian Democratic Party (Partito Democratico, PD), winning with 67.5% of the vote.

On February 22, 2014, following the resignation of Enrico Letta and after a vote by a large majority within the PD, he became President of the Council of Ministers (Prime Minister of Italy), the youngest in the history of Italy. After the negative result of the constitutional referendum on December 4, 2016, Matteo Renzi resigned as Prime Minister. 
 
In April 2017, almost two million voters took part in the primary elections for Secretary of the PD. Renzi was re-elected with 69% of the votes cast. Following the results of the Italian parliamentary election, in March 2018 he resigned as Leader of the PD.
 
Matteo Renzi is currently Senator for the Electoral College of Florence, Scandicci, Signa, Lastra a Signa and Impruneta. His activity as a politician has been accompanied by his writing, which includes the books Fuori! (2011), Stilnovo (2012), Oltre la rottamazione (2013), and Avanti! Perché l’Italia non si ferma (2017). He has also taught at Stanford's Florence campus in recent years. 
Matteo Renzi, former Prime Minister of Italy speaker
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Timothy Josling, a professor emeritus at the former Food Research Institute and an affiliate of The Europe Center known for his encyclopedic knowledge of international agricultural policy, died on Nov. 27.

Timothy Josling, a Stanford professor emeritus of agricultural economics, died at his home in Davis, California, on Nov. 27 after a two-year battle with cancer. He was 78.

Josling, professor emeritus at the former Food Research Institute, was a prolific scholar in agricultural economics. He was known for his humor, patience and devotion to his work and family, according to his relatives and colleagues.

“My dad was one of those people who had an answer to every question,” said his daughter, Catherine Josling. “I loved asking him questions because I knew whether he knew the answer or not, he would confidently answer the question. He also had a wonderful sense of humor – you could always count on him for a witty retort.”

Tim Josling portrait

A walking encyclopedia

Originally from London, England, Josling joined Stanford in 1978 to teach at the former Food Research Institute, which was founded in 1921 by Herbert Hoover to investigate the issues of food production, distribution and consumption.

Josling’s research interests centered on agricultural policies and international trade regulations – and he was admired by his colleagues for his wide breadth of knowledge on these topics.

“Tim Josling was a walking encyclopedia of international agricultural institutions, and he made lasting contributions in the fields of international trade and policy analysis,” said Walter P. Falcon, who directed the Food Research Institute from 1972 to 1991 and recruited Josling to join the faculty. “He was also uncommonly broad. We used to jokingly – but seriously – say that if one wanted 10 pages overnight of really good analysis on any economics topic, best to call Tim.”

Among his many contributions to the field of agricultural economics, Josling is most known for developing the “producer subsidy equivalent approach,” a measure that helps countries understand how much of a farmer’s earnings was created by agricultural policy. Josling initially developed the formula, also known as the “PSE,” for the Food and Agriculture Organization of the United Nations, and it has since been adopted by the Organization for Economic Cooperation and Development, the United States Department of Agriculture and the World Trade Organization (WTO).

“The Josling PSE is used to this day,” said his colleague Scott Pearson, who served on the Stanford faculty as a professor of agricultural economics from 1968 until his retirement in 2002 and as director of the Food Research Institute from 1991 to 1996. “The PSE helps governments understand the costs of agricultural protection and support.”

Dedicated scholar

From 1993 to 1996, Josling served as the director for the Center for European Studies at the Freeman Spogli Institute for International Studies (FSI). When the Food Research Institute closed in 1996, he went on to co-convene the European Forum, now The Europe Center, until he retired in 2003.

Throughout retirement, Josling remained active on campus as a senior fellow, by courtesy, at FSI. Until 2016, he taught a course on the economics of the WTO for the Program in International Relations and would regularly meet with his students at the Europe Center’s offices, said program administrator Karen Haley.

Josling’s recent publications include the three-volume Handbook on International Food and Agricultural Policies, which was published in 2018. In 2015, he co-authored Transatlantic Food and Agricultural Trade Policy: 50 Years of Conflict and Convergence with his long-time collaborator, Stefan Tangermann of the University of Göttingen in Germany.

“One could discuss the most crazy ideas with him and develop them jointly into workable hypotheses and proposals,” said Tangermann, who first met Josling in 1973. Over the next 40 years, the pair developed a close professional partnership and wrote more than 50 publications together, including two major books.

“From the 1980s on, Josling and Tangermann were considered the profession’s leaders in explaining European agricultural policy and in discussing its implications for policymakers,” said Pearson.

Josling was a member of the International Policy Council on Food and Agricultural Trade and former chair of the executive committee of the International Agricultural Trade Research Consortium. He also held a visiting professorship at the University of Kent, in the United Kingdom, and was a past president of the UK Agricultural Economics Association. In 2004, he was made a Fellow of the American Agricultural Economics Association.

Despite his accomplishments, Josling was “very self-effacing,” said his colleague and friend Christophe Crombez, a senior research scholar at the Europe Center. “Tim was not someone who sought the spotlight.”

Quintessential English professor; avid sports fan

Prior to joining Stanford, Josling taught at the London School of Economics and the University of Reading in England.

Josling received a BSc in agriculture from the University of London (Wye College), an MSc in agricultural economics from the University of Guelph, Canada, and a PhD in agricultural economics from Michigan State University.

His family described him as the “quintessential English professor,” and according to Falcon, “He never lost all of his English ways. If he were to walk in the door you would think he belonged in a Shakespeare play – he looked the part of an English actor.”

Josling also loved sports, including cricket and thanks to Pearson, baseball as well.

Pearson remembers taking Josling to his first game at Stanford’s Sunken Diamond in the late 1970s: “At his first game, Tim offered a suggestion. He noted that it would be much more difficult for the batter to hit the baseball if only the pitcher – no, Tim, he was not called the hurler – would bounce the ball in front of home plate. I had to tell him that, alas, this would not work in American baseball.”

For years, Josling and his wife, Anthea, also had season tickets for Stanford football as well as for women’s and men’s basketball.

Josling was devoted to his family and garden. In 2003, he and Anthea moved to the hills in Los Gatos. There, he grew a variety of vegetables and tended to goats and chickens, as well as caring for several cats and dogs. His also enjoyed sailing, photography and travel. In early 2018, the Joslings moved to Davis to be closer to his daughter and grandchildren.

“What I liked most about Tim was his good nature,” Falcon said. “Tim could find the bright side of things, when the rest of us had trouble.”

Josling is survived by his wife, Anthea; his children, Catherine, BS ’03, and John Mark, BS ’99, and their spouses, Amiel Sagpao and Jessica Smith, as well as two grandchildren, Claire Sagpao and Andrew Sagpao. Plans for a celebration of life in the new year are pending. In lieu of flowers, the family request donations in Josling’s name to the Cancer Research Institute.

 

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Abstract:

Russia has evolved into an autocracy under Putin's 18-year long rule. The political landscape resembles a desert with just a few oases of relatively strong civil initiatives and political movements. Under these circumstances, people who are eager to continue their activities inside Russia - be it cultural or philanthropic projects - face hard moral choices to either collaborate with the regime or refuse to do so and sacrifice many opportunities along the way. In light of these circumstances, is there any ground for optimism? What are the necessary pre-conditions for strong movements in Russia? What are the visions for post-Putin Russia? Zhanna Nemtsova, the founder of the Boris Nemstov Foundation for Freedom and a news show/anchor for the Deutsche Welle broadcaster shares her insights into the current state of affairs in Russia during this special lunchtime event hosted by the Center on Democracy, Development, and the Rule of Law together with the Center for Russian, East European and Eurasian Studies.

 

Speaker Bio:

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zhanna nemstova1
Zhanna Nemtsova is a Russian journalist currently working at Deutsche Welle, a German international broadcaster. At Deutsche Welle, Nemtsova hosts the weekly Russian-language program "Nemtsova.Interview," which features discussions on current events. Nemtsova founded the Boris Nemtsov Foundation for Freedom to promote the ideas of freedom and education and to preserve her father's liberal political legacy after he was assassinated in 2015. The Foundation awards the Boris Nemtsov Prize to courageous Russians for their demonstrated dedication to fighting for democratic rights in Russia, hosts the annual Boris Nemtsov Forum in Berlin and supports Russian political prisoners and asylum seekers. On May 10 the Boris Nemtsov Foundation, in cooperation with Charles University in Prague, launched the Boris Nemtsov Center for Russian Studies. Nemtsova holds a bachelor’s of science degree in economics with a minor in foreign languages from the Moscow State Institute of International Relations.

 

 

 

 

Zhanna Nemtsova Founder of the Boris Nemstov Foundation for Freedom
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Eloise Duvillier

Eloise Duvillier is the Program Manager of the Program on Democracy and the Internet at the Cyber Policy Center. She previously was a HR Program Manager and acting HR Business Partner at Bytedance Inc, a rapidly-growing Chinese technology startup. At Bytedance, she supported the globalization of the company by driving US acquisition integrations in Los Angeles and building new R&D teams in Seattle and Silicon Valley. Prior to Bytedance, she led talent acquisition for Baidu USA LLC’s artificial intelligence division. She began her career in the nonprofit industry where she worked in foster care, HIV education and emergency response during humanitarian crises, as well as helping war-torn communities rebuild. She graduated from University of California, Berkeley with a bachelor’s degree in Development Studies, focusing on political economics in unindustrialized societies.

Program Manager, Program on Democracy and the Internet
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At 11am on November 11, 1918, the armistice that effectively ended the First World War was signed. What came to be known as “The Great War” had a profound and lasting impact on the cultural fabric of the nations involved: as Paul Fussell wrote, “its dynamics and iconography proved crucial to the political, rhetorical, and artistic life of the years that followed; while relying on inherited myth, war was generating new myth.” Over the course of the 20th century, the concept of war evolved beyond historically traceable moments and events to include the consideration of war as site and influence shaping every aspect of lived experience. This conference seeks to examine ways in which literature and the arts have taken up and taken apart war and the myths surrounding it -- grappling with it both as subject and context while also considering the ways in which the experience of war molded, mutilated, and morphed artistic forms. Though the word “centennial” often rings of monolithic celebration, it is equally an opportunity to highlight the attempts of writers and artists to contain, contend, or survive war and to question and problematize preconceptions and existing views of war by investigating their inherently bipolar nature.

November 10, 2018 (Day 2)
SCHEDULE:

  • 9 – 11am - 2nd PANEL
    Chair: Jennifer Scappettone (University of Chicago, Associate Professor)
     
  • Aubrey Knox (CUNY, PhD Student)
    "The Regulated Body: The Grand Palais as Military Hospital in World War I"
  • Joanna Fiduccia (Reed College, Assistant Professor)
    "A Destructive Character: Alberto Giacometti’s Crisis of the Monument"
  • Hadrien Laroche (INHA, France, Philosopher and Researcher)
    "Duchamp's waste: Trauma, Violence and Aesthetics"
     
  • 11 - 11.30am – COFFEE BREAK
     
  • 11.30am - 12.45pm – KEYNOTE ADDRESS

Jay Winter (Yale University, Emeritus Professor)
"All the Things We Cannot Hear: Silences of the Great War"

  • 12.45am – 2pm – LUNCH BREAK
     
  • 2 - 4.30pm - 3rd PANEL
    Chair: Peter Stansky (Stanford University, Emeritus Professor)
     
  • Martin Löschnigg (University of Graz, Austria, Professor)
    "‘The extreme fury of war self-multiplies’: First World War Literature and the Aesthetics of Loss"
  • Ron Ben-Tovim (Ben Gurion University, Israel, Post-Doc), Boris Shoshitaishvili (Stanford University, PhD Student)
    "Re-Enchanting the World after War: J. R. R. Tolkien, David Jones, and the Revision of Epic"
  • Anna Abramson (MIT, Post-Doc)
    "Atmospheric Myths of The Great War"
  • Isaac Blacksin (UC Santa Cruz, PhD Student)
    Senseless Encounter, Immutable Sense: The Contradictions of Reporting War

 

  • 4.30 – 4.45pm – COFFEE BREAK
     
  • 4.45 – 6pm – KEYNOTE ADDRESS

Alexander Nemerov (Stanford University, Professor)
"A Soldier Killed in the First World War"

For more info,  please email: massucco@stanford.edu

Sponsored by:  the Division of Literatures, Languages, and Cultures;  Stanford Department of Art and Art History; Theater and Performance Studies; Stanford Humanities Center; The Europe Center; Dept. of French and Italian; Dept. of History; Dept. of German Studies; and the Dean's Office of Humanities and Sciences.

 

Stanford Humanities Center
424 Santa Teresa Street
Stanford, CA 94305

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At 11am on November 11, 1918, the armistice that effectively ended the First World War was signed. What came to be known as “The Great War” had a profound and lasting impact on the cultural fabric of the nations involved: as Paul Fussell wrote, “its dynamics and iconography proved crucial to the political, rhetorical, and artistic life of the years that followed; while relying on inherited myth, war was generating new myth.” Over the course of the 20th century, the concept of war evolved beyond historically traceable moments and events to include the consideration of war as site and influence shaping every aspect of lived experience. This conference seeks to examine ways in which literature and the arts have taken up and taken apart war and the myths surrounding it -- grappling with it both as subject and context while also considering the ways in which the experience of war molded, mutilated, and morphed artistic forms. Though the word “centennial” often rings of monolithic celebration, it is equally an opportunity to highlight the attempts of writers and artists to contain, contend, or survive war and to question and problematize preconceptions and existing views of war by investigating their inherently bipolar nature.

November 9, 2018 (Day 1)
SCHEDULE:

  • 4 – 4.30pm – OPENING REMARKS
  • 4.30 - 7pm - 1st PANEL

Chair: Russell Berman (Stanford University, Professor)

  • Greg Chase (College of the Holy Cross, Lecturer)
  • ‘Death is not an event of life’: How Wittgenstein’s War Experience Re-Shaped His Philosophy
  • Victoria Zurita (Stanford University, PhD Student)
  • Ironic prospects: hope in Jean Giono’s To the Slaughterhouse
  • André Fischer (Auburn University, Assistant Professor)
  • Politics by other means: War photography in the work of Ernst Jünger
  • Nicholas Jenkins (Stanford University, Associate Professor)

 

For more info,  please email: massucco@stanford.edu

Sponsored by:  the Division of Literatures, Languages, and Cultures;  Stanford Department of Art and Art History; Theater and Performance Studies; Stanford Humanities Center; The Europe Center; Dept. of French and Italian; Dept. of History; Dept. of German Studies; and the Dean's Office of Humanities and Sciences.
 

Stanford Humanities Center
424 Santa Teresa Street
Stanford, CA 94305

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Beth Duff-Brown
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Preeclampsia is a serious complication of pregnancy that affects 5 to 10 percent of all pregnancies — over 8 million a year worldwide — and claims the lives of 76,000 mothers and half a million babies each year.

The condition causes hypertension and abnormal protein in the urine, and has few effective preventive or therapeutic strategies. The clinical abnormalities usually resolve completely after delivery, but recent research shows that women who have had preeclampsia have higher rates of heart disease later in life, for reasons that are poorly understood.

That’s where Mark HlatkyVirginia Winn, and their Stanford Medicine research team come in. They were recently awarded a 4-year, $6 million NIH grant from the National Heart, Lung and Blood Institute to study the links between preeclampsia and the subsequent risk of atherosclerotic cardiovascular disease (ASCVD) as women grow older.

“The goal of this study is to improve cardiovascular health in women, by learning how pregnancy affects heart disease later in life,” said Hlatky, a Stanford Health Policy fellow. “We hope that shedding new light on these links can lead to better prevention and treatment.”

The interdisciplinary study called EPOCH — Effect of Preeclampsia On Cardiovascular Health — could eventually help millions of women and their clinicians worldwide.

“Since about 85 percent of women become pregnant at some point during their lives, and heart disease is the leading cause of death in women, determining how pregnancy complications might increase the risk of heart disease later in life could be very important,” said Hlatky, a professor of health research and policy and of cardiovascular medicine. “If there is a specific biomarker ‘signature’ of heart disease risk in women who have had preeclampsia, it would open up new possibilities for risk assessment and better treatment to prevent heart attacks and strokes.”

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Hlatky and his co-principal investigator, Stanford high-risk obstetrician Winn, note that a history of preeclampsia doubles the woman’s risk of future heart disease and stroke, and triples her risk of hypertension. And these adverse consequences occur at younger ages than in women who never developed the condition during pregnancy.

"The dramatic physiologic changes that happen during pregnancy are indeed remarkable," said Winn, the Arline and Pete Harman faculty scholar in the Department of Obstetrics and Gynecology. "This study highlights how complications that occur in pregnancy impact women's health beyond pregnancy." 

The pathogenic links between preeclampsia early in life and ASCVD late in life have been difficult to investigate because the process develops over decades, the authors said. And few clinicians are aware of the link between the condition and late ASCVD risk and there are no validated biomarkers for this process.

Preliminary data that contributed to the application of the project was a direct result of Winn’s endowed Arline and Pete Harman Faculty Scholar award and funding from the Stanford Maternal and Child Health Research Institute and the Stanford Cardiovascular Institute.

The 4-year grant will support a multi-disciplinary research team in taking a life-course approach. The EPOCH study will enroll three cohorts of women at distinct points in the natural history of the disorder: during pregnancy in their reproductive years; during the long, asymptomatic period in mid-life; and the ultimate development of ASCVD in later life.

“It’s very difficult to study the effects of early life events on the development of diseases late in life, since they are separated by 40 years or more,” Hlatky said. “We don’t have reliable health records in the United States from 40 or more years ago, so it’s a challenge for American researchers.” This is why, he said, the EPOCH study includes researchers from Denmark, which has a national health system, complete medical data of their citizens since the 1970’s, and a national biobank that will allow study of later life events.

The first cohort of women will include some of those who are already part of the Stanford March of Dimes Prematurity Research Center. The center, led by David Stevenson began recruiting women in 2011 to study pregnancy from the first trimester through delivery. The study has collected a wide array of “omics” measures at multiple time points: metabolomics, proteomics, cell-free RNA, the microbiome and immune cells for analysis, as well as collection of amniotic fluid, cord blood, and the placenta. The pregnancy cohort will enroll additional women who are cared for at Lucile Packard Children’s Hospital for treatment of preeclampsia, about 100 in all, plus a matched group with uncomplicated pregnancies.

This is where it gets pretty technical — but also pretty cool

The researchers will collect high-dimensional “omic” biomarker data to assess the pathophysiology of preeclampsia and its relationship to cardiovascular function and disease. They’ll assess cell signaling pathways using single-cell immune profiling (CyTOF) methods in the lab of Brice Gaudilliere, an assistant professor of anesthesia.

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They will then analyze the cell-free RNA profiles using methods developed by co-investigator Stephen Quake, a professor of bioengineering and applied physics, and co-president of the Chan Zuckerberg Biohub. They will assess metabolomics using novel methods also developed at Stanford by co-investigator Michael Snyder,  professor and chair of genetics.

Stanford data scientists, including co-investigators, Robert Tibshirani and Nima Aghaeepour, have been at the forefront of developing and applying novel statistical and bioinformatic approaches, which the team will use to analyze the torrents of data that can now be collected by modern “omics” technologies from individual clinical research subjects.

“The EPOCH study is truly interdisciplinary — we are bringing together faculty from eight different departments to study a major problem in women’s health.”

The second, mid-life cohort will be recruited from women who had a pregnancy complicated by preeclampsia. Marcia Stefanick, professor of medicine in the Stanford Prevention Research Center, will use the Stanford Medicine Research Data Repository (STARR), which contains electronic records from more than 1.6 million patients since 1995, to identify eligible women. Stefanick and the EPOCH team will recruit 200 pre-menopausal women who had either a pregnancy complicated by preeclampsia or an uncomplicated pregnancy.

The third, late-life cohort of women will be identified in the Danish National Biobank by Stanford visiting professor Mads Melbye. Samples will be retrieved from women who had preeclampsia early in life and ASCD later in life, as well as a set of matched control subjects, and analyzed in Stanford laboratories.

“We’re not quite sure whether the physiologic challenges of pregnancy that result in preeclampsia simply reveal underlying cardiovascular risk, or causes change that leads to the increased risk in later life,” Winn said. “The EPOCH study will identify unique aspects of preeclampsia that links it to later ASCVD, opening potential novel approaches to improve women’s health.”

The EPOCH study brings together investigators from eight departments. Additional faculty include Gary Shaw and Seda Tierney (Pediatrics), Martin Angst (Anesthesia), Nicholas Leeper (Surgery) and Heather Boyd (Danish Biobank).

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