About the event: This talk will describe two projects, one in the middle and one just getting under way, both related to the benefits and harms of COVID-19 control measures.

The first project aims overall to provide a rigorous estimate of the benefits of COVID-19 control measures prior to vaccination in terms of COVID-19 deaths averted. Prominent existing analyses (T. Bollyky et al., 2023, Lancet, and empirical estimates in Macedo and Lee In COVID’s Wake 2025, suggest that this benefit was nonexistent — that adoption of anti-COVID restrictions had no measurable impact on COVID-19 deaths — but suffer from major methodological limitations and defects. This part of the talk will lay out the conditions for an appropriate analysis of this question and will describe planned work to conduct such an analysis.

The second project, with CISAC fellow Johannes Ponge, aims to assess the degree to which existing pandemic response plans incorporate consideration of unintended consequences of these measures in sectors such as the economy, education, and mental health, and to create tools to aid decision makers in tracking such impacts in future pandemics.

About the speaker: Marc Lipsitch is an infectious disease epidemiologist, mathematical modeler, and microbiologist who has been actively working on biosecurity for more than a decade. His science focuses on pandemic preparedness and response, evaluation of disease control measures, and the impact of pathogen evolution on human disease. His biosecurity work to date has focused on surveillance design, pandemic response, and prevention through the regulation of risky research. He joined Stanford this year after 26 years at Harvard Chan School of Public Health, where he led the Center for Communicable Disease Dynamics, and 4 years at the US CDC, where he was founding Director for Science and then Senior Advisor at the Center for Forecasting and Outbreak Analytics.
 

 All CISAC events are scheduled using the Pacific Time Zone.

No filming or recording without express permission from speaker.